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212 Ohio Street Suite 2 Buffalo, NY Monday-Saturday: 10AM-9PM Sunday: 10AM-7PM
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A Mission Bigger Than Weed

Founded by Michael Nicosia in 2019, Lions Mane Infusions was built around a straightforward but ambitious goal: enhance the lives of one million people through plant-based and functional mushroom products. That mission has shaped everything about how the brand operates — from the years of research and development before a single product hit a shelf, to the emphasis on education and community empowerment that runs through everything they do.

This isn’t a brand that stumbled into wellness language for marketing purposes. Lions Mane Infusions spent years studying the intersection of plant-based medicine and functional mushrooms before bringing products to market. The cannabis came later, informed by the same philosophy that drove the mushroom work from the beginning.

Why Lion’s Mane?

Lion’s Mane mushrooms have been used for centuries in traditional medicine for their cognitive and neuroprotective properties. Unlike synthetic nootropics that offer short-term stimulation with side effects, Lion’s Mane works with the body — supporting brain health, promoting nerve growth, protecting against cognitive decline, and helping reduce anxiety. It’s a functional ingredient with a long track record and a growing body of modern research behind it.

The connection to cannabis isn’t arbitrary. Both the cannabis plant and Lion’s Mane mushroom interact with the body’s natural systems in ways that can complement each other — and Lions Mane Infusions has built their brand around exploring that intersection thoughtfully and honestly.

Built Deliberately, Not Quickly

The Lions Mane Infusions timeline reflects a brand that took its time. Research and development from 2019 through 2022. An online CBD shop launched in 2023. Retail partnerships beginning in 2024. Strategic expansion in 2025. That’s a measured, intentional growth path from a founder who clearly believed that getting it right mattered more than getting it out fast.

For customers who care about the integrity behind what they’re buying, that kind of patience is its own kind of endorsement.

Why We Carry Lions Mane Trees

At Mammoth, we carry Lions Mane Trees because the philosophy behind the brand is genuine and the products reflect it. Michael Nicosia set out to promote health and wellness through plant-based medicine, and the Jungle Juice pre-rolls at Mammoth are an expression of that mission in a format our customers can experience directly. It’s a New York State brand doing something different, and doing it with care.

Ask Us About Lions Mane Trees

Our staff can walk you through the Lions Mane Trees products currently available at Mammoth, including the Jungle Juice pre-rolls. Come in and ask — this is one worth learning about.

OPERATING HOURS

MON – SAT // 10AM – 9PM
SUNDAY // 10AM – 7PM

ACCEPTED PAYMENT

CASH // ATM // DEBIT CARD
PAY BY BANK // GIFT CARDS

SERVICE AREA

BUFFALO, NY
+ SURROUNDING AREAS

Check Out Our Reviews

Great spot! Staff is super friendly and knowledgeable. Their products are always stocked and have such variety. The area is a plus too!

Madison M

Friendly experience my first time here, they made me feel welcomed, and the interior is tasteful and comfortable. I would recommend them to anyone who is new to recreational or otherwise.

Tucker R

Great dispensary. Amazing friendly and helpful staff! Great selection for a variety of consumption methods. Definitely recommend stopping by and supporting if you’re in the area!

Dominique W

Moved into the neighborhood and this place is super convenient. Great staff. Pre-roll Tuesday is the best.

Traci Fell

An awesome place to get some bud. Staff is very knowledgeable and friendly. Extremely clean. Highly recommend

Travis R

Great experience. I’m so happy with the products we got. The staff were super kind and knowledgeable, felt like I got a great rundown of what I was interested in buying.

Natasha N

Great products, and staff that is very friendly and super informative. Great spot for your medicinal needs, check it out.

Cody S

Loved the first trip here. Definitely will be back. The budtender was great and their recommendations were amazing. Can’t wait to go back and will be recommending this to my friends.

Julie F
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